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JPS014
CAS No. : 2669785-76-4
Biological Activity：JPS014 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 degrades class I histone deacetylase (HDAC). JPS014 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells.
Research Area：Cancer
Targets：HDAC|PROTACs
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;Pivanex;Crotonoside;MPT0B390;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;RSC133;HDAC1/6-IN-1;HDAC/HSP90-IN-4;PROTAC PARP1 degrader;HDAC-IN-4;MD-224;FKBP12 PROTAC dTAG-7;SJ10542;MS8815;HDAC-IN-27;1-Alaninechlamydocin;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;SJ995973;SKLB-23bb;Tacedinaline
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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