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JMV 449

CAS No. : 139026-66-7

Biological Activity：JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC₅₀ of 0.15 nM for inhibition of [¹²⁵I]-neurotensin binding to neonatal mouse brain and an EC₅₀ of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse^[2].

Research Area：Neurological Disease

Targets：Neurotensin Receptor

Related Small Molecules:NTRC-824;THX-B;ML314;SORT-PGRN interaction inhibitor 1;AF38469;Kinetensin;Contulakin G;SR 142948;[Lys8, Lys9]-Neurotensin (8-13);Neurotensin;SBI-553;AF40431;[D-Trp11]-Neurotensin;LM11A-31 dihydrochloride;VGD071;Neurotensin(8-13)

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