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JH295
CAS No. : 1311143-71-1
Biological Activity：JH295 is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 inhibits cellular Nek2 via alkylation of Cys22. JH295 is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint.
Research Area：Cancer
Targets：Others
Related Screening Libraries:Bioactive Compound Library Plus;
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