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Henatinib
CAS No. : 1239269-51-2
Biological Activity：Henatinib is an orally active small-molecule multikinase inhibitor that has demonstrated broad and potent antitumor activities. Henatinib inhibits the activity of VEGFR-2, c-kit, PDGFR with IC50 values of 0.6 nM, 3.3 nM and 41.5 nM, respectively. Henatinib significantly inhibits VEGFR-2 phosphorylation and its downstream signal pathway in human umbilical vein endothelial cells (HUVECs).
Research Area：Cancer
Targets：VEGFR|c-Kit|PDGFR
Related Small Molecules:(Z)-FeCP-oxindole;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;Pexidartinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530
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