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HBX 41108

CAS No. : 924296-39-9

Biological Activity：HBX 41108 is an uncompetitive inhibitor of ubiquitin-specific protease 7 (USP7) with an IC₅₀ of 424 nM. HBX 41108 inhibits USP7-mediated p53 deubiquitination to stabilize p53 and inhibits cancer cell growth. HBX 41108 induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines^[2].

Research Area：Cancer

Targets：Deubiquitinase|Apoptosis

Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Ubiquitination Compound Library;

Related Small Molecules:Physalin A;SJB3-019A;Bomedemstat ditosylate;SJB2-043;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;USP7-IN-1;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib

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