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GSK3179106

CAS No. : 1627856-64-7

Biological Activity：GSK3179106 is an orally active and selective RET kinase inhibitor with IC₅₀s of 0.4 nM, 0.2 nM for human RET and rat RET, respectively. GSK3179106 has the potential for irritable bowel syndrome (IBS) through the attenuation of post-inflammatory and stress-induced visceral hypersensitivity.

Research Area：Metabolic Disease|Inflammation/Immunology

Targets：RET

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Clinical Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Liver Cancer Compound Library ;

Related Small Molecules:RET-IN-18;Zeteletinib;RET-IN-5;Pyrazoloadenine;trans-Pralsetinib;PF 477736;BT-13;RET-IN-8;AD80;JNJ-38158471;Amuvatinib hydrochloride;RET-IN-11;TRK II-IN-1;RET-IN-10;RET-IN-17;RET-IN-7;RET-IN-13;TG101209;WHI-P180;TAS05567;RET-IN-14;FLT3/ITD-IN-4;Pz-1

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