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Freselestat
CAS No. : 208848-19-5
Biological Activity：Freselestat (ONO-6818) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat has a potent anti-inflammatory activity[2][3][4].
Research Area：Inflammation/Immunology
Targets：Elastase
Related Small Molecules:Cyclotheonellazole A;JCP174;BAY-678 racemate;Elastase-IN-1;19α-Hydroxyasiatic acid;Tutuilamide A;MDL 101146;Lodelaben;GW311616 hydrochloride;Elastatinal;DMP 777;BAY-85-8501;FK706;SSR69071;Elastase from porcine pancreas;Secologanoside;Tyrosinase/elastase-IN-1;ZD8321;ZD-0892
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