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Foxy-5 TFA
Biological Activity：Foxy-5 TFA, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 TFA triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 TFA effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[2][3][4].
Research Area：Cancer
Targets：Wnt
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus; Bioactive Compound Library Plus;Peptide Library;
Related Small Molecules:Wnt/β-catenin agonist 1;ARUK3001185;Gallocyanine chloride;Fz7-21;Wnt/β-catenin agonist 4;JW74;IQ 1;Heparan Sulfate;ETC-159;Laduviglusib (GMP);KY-05009;HLY78;Wnt-C59;Wogonin;NCB-0846;KY-02327;Echinacoside;JW67;IWP-4;Triptonide;Prodigiosin;BML-284 hydrochloride;Astragaloside I;β-catenin-IN-3;NLS-StAx-h;FzM1.8;KY19382;NSC668036
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