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EDP-305
CAS No. : 1933507-63-1
Biological Activity：EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 shows a potent and consistent antifibrotic effect. EDP-305 can be used for primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH) research[2].
Research Area：Inflammation/Immunology
Targets：Phosphatase|FXR|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Nuclear Receptor Compound Library;
Related Small Molecules:SR9186;AMG-208;DY268;GNF362;ZLDI-8;Uralenol;FXR agonist 4;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;SHP504;Trimyristin;SHP099 hydrochloride;Chenodeoxycholic Acid-d9;Galeterone;MY10;Ranitidine;Bergapten;PTP1B-IN-3 diammonium;Ginsenoside Rd;Calyculin A;LMPTP inhibitor 1 dihydrochloride;[pTyr5] EGFR (988-993) (TFA);AS1810722;RMC-3943
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