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Dynole 34-2
CAS No. : 1128165-88-7
Biological Activity：Dynole 34-2 is a dynamin GTPase inhibitor (IC50s=6.9 and 14.2 µM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[2].
Research Area：Cancer
Targets：Dynamin
Related Small Molecules:Schaftoside;Dynamin inhibitory peptide TFA;DynaMin inhibitory peptide, myristoylated;Drp1-IN-1;Dynole 2−24;Mdivi-1;Hydroxy-Dynasore;Dynasore
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