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Dasabuvir

CAS No. : 1132935-63-7

Biological Activity：Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC₅₀ values of 7.7 and 1.8 nM, respectively.

Research Area：Infection

Targets：HCV|DNA/RNA Synthesis

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Anti-Hepatitis C Virus Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;EMA-Approved Drug Library;Human Metabolite Library;

Related Small Molecules:Ametantrone;HCV-IN-30;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;HCV-IN-38;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;Sennidin A;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;HCV-IN-31;6-Thio-2′-Deoxyguanosine;Radalbuvir;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;FGI-106 tetrahydrochloride;TH287 hydrochloride;BMS-986144;Oenothein B

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