For research use only. We do not sell to patients.
Crenigacestat
CAS No. : 1421438-81-4
Biological Activity：Crenigacestat (LY3039478) is an orally active Notch and γ-secretase inhibitor, with an IC50 of 1 nM in most of the tumor cell lines tested[2][3][4].
Research Area：Cancer
Targets：Notch|γ-secretase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;
Related Small Molecules:γ-Secretase modulator 4;ELN318463;ZLDI-8;Aβ42-IN-1 free base;Fosciclopirox;FLI-06;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;JI051;Aβ42-IN-2;Demcizumab;DAPT (GMP);Notch inhibitor 1;BPN-15606;Tarextumab;Notch 1 TFA;Bruceine D;LY-411575 (isomer 3);Psoralidin;BMS 433796;YO-01027 (GMP);BI-1408
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
