CRBN modulator-1

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CRBN modulator-1

CAS No. : 2407829-65-4

Biological Activity:CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM.

Research Area:Cancer

Targets:Ligands for E3 Ligase

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cancer Compound Library;Ubiquitination Compound Library;E3 Ligase Ligand Library;

Related Small Molecules:(S,R,S)-AHPC TFA;cIAP1 ligand 4;(S,R,S)-AHPC-Me;cIAP1 ligand 2;E3 ligase Ligand 23;VH032;BC-1215;VH032-cyclopropane-F;KB02-COOH;N-Boc-SBP-0636457-OH;SJPYT-195;TD-106;CC-885;VH032-OH

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