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Ciglitazone
CAS No. : 74772-77-3
Biological Activity：Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells[2][3][4].
Research Area：Cancer|Cardiovascular Disease
Targets：PPAR
Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;Mifobate;Daidzein-d4;MK-886;CP-775146;FK614;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;Norathyriol;Saroglitazar;GW 9578;Elafibranor;ST247;Bilobetin
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