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Chiauranib
CAS No. : 1256349-48-0
Biological Activity：Chiauranib (CS2164) is an orally active multi-target inhibitor against tumor angiogenesis. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF-1R, with IC50 values ranging from 1-9 nM. Chiauranib has strongly anticancer effects.
Research Area：Cancer
Targets：VEGFR|Aurora Kinase|c-Kit|c-Fms|PDGFR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:(Z)-FeCP-oxindole;DB0614;VEGFR-2-IN-24;BMS-690514;AT9283;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Foretinib;ZM323881 hydrochloride;Zeteletinib;Pexidartinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;Barasertib-HQPA
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