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CH6953755

CAS No. : 2055918-71-1

Biological Activity：CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC₅₀ of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo.

Research Area：Cancer

Targets：Src

Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;

Related Small Molecules:KB SRC 4;Tirbanibulin dihydrochloride;Bafetinib;p60c-src substrate II;Caffeic acid-pYEEIE TFA;PP2;PP58;ENMD-2076 Tartrate;Fenlean;TL02-59;A-770041;PF 477736;PD166326;Masitinib;Lyn peptide inhibitor TFA;SM1-71;β-Hydroxyisovalerylshikonin;HG-7-85-01;Squarunkin A hydrochloride;1-NM-PP1;MNS;TG 100801;Scutellarein;TG 100572;AMG-47a

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