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Ceritinib
CAS No. : 1032900-25-6
Biological Activity:Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency[2].
Research Area:Cancer|Endocrinology
Targets:Insulin Receptor|IGF-1R|Anaplastic lymphoma kinase (ALK)
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Therapy Drug Library ;Angiogenesis-Related Compound Library;Rare Diseases Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:ALK-IN-9;KRCA-0008;AGL-2263;Alectinib-d8;MS4078;TL13-22;AZ7550 Mesylate;KU14R;NVP-TAE 684;Picropodophyllotoxin-d6;SU4984;Chromeceptin;ALK5-IN-30;TL13-112;I-OMe-Tyrphostin AG 538;ALK-IN-22;Ganitumab;HNMPA-(AM)3;Alectinib;ALK-IN-12;S961 TFA;OI338;Entrectinib;ALK kinase inhibitor-1
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