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Camptothecin
CAS No. : 7689-03-4
Biological Activity：Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].
Research Area：Cancer|Infection
Targets：Topoisomerase|Fungal|MicroRNA|Influenza Virus|ADC Cytotoxin|Antibiotic|Apoptosis
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