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C188
CAS No. : 823828-18-8
Biological Activity：C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM).
Research Area：Cancer
Targets：STAT
Related Small Molecules:Cirsilineol;Ochromycinone;C188-9;STAT3-IN-10;Niclosamide monohydrate;STAT3-IN-1;STAT3 degrader-1;PM-81I;Morusin;Nifuroxazide-13C6;AS1810722;α7 nAchR-JAK2-STAT3 agonist 1;HP590;Eupalinolide K;STAT3-IN-11;(R)-Reticuline-d3;JAK-IN-23;UC-514321;MM-206;SH-4-54;Bruceantinol;Scutellarin;Cucurbitacin I;ENMD-1198;SH5-07
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