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Brompheniramine maleate
CAS No. : 980-71-2
Biological Activity：Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research[2][3][4].
Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease
Targets：Calcium Channel|mAChR|Histamine Receptor|Sodium Channel|Potassium Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Targeted Diversity Library;Antidepressant Compound Library;Calcium Channel Blocker Library;Sodium Channel Blocker Library;Potassium Channel Compound Library;Human Metabolite Library;Non-steroidal Anti-Inflammatory Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:VU0357017 hydrochloride;Benidipine hydrochloride;Lu AE98134;CaV1.3 antagonist-1;14-Deoxyandrographolide;TBPB;Kv3 modulator 2;Imidafenacin;Zandatrigine;Sabcomeline;(Rac)-MEM 1003;Tripelennamine;Glaucine;Veratridine;MK-6884;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Pinacidil;MRS 1523;GX-674
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