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BMS-986020 sodium
CAS No. : 1380650-53-2
Biological Activity：BMS-986020 (AM152) sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively[2]. BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF)[3].
Research Area：Metabolic Disease|Inflammation/Immunology
Targets：LPL Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Rare Diseases Drug Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:GSK2018682;Ozanimod hydrochloride;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;S1P2 antagonist 1;S1P1 agonist III;Ceralifimod;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;1-Oleoyl lysophosphatidic acid;Ex26;RP-001 hydrochloride;VPC 23019;CYM-5541;LPA1 receptor antagonist 1;Autotaxin-IN-6;Zectivimod;CYM5442 hydrochloride;PF-543 Citrate;LPA2 antagonist 1;LPA2 antagonist 2
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