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Bicyclol
CAS No. : 118159-48-1
Biological Activity：Bicyclol(SY 801) is a anti-hepatitis drug.
Target: HBV
Oral administration of bicyclol normalized the elevated serum transaminases (ALT, AST) by approximately 50% in chronic viral hepatitis B and C, and also showed certain level of inhibiting HBV and HCV replication. No noticeable adverse reaction has been observed. In combination therapy of bicyclol with interferon alpha, lamivudine and adefovir dipivoxil in HBV or HCV, bicyclol may potentiate the anti-viral efficacy and reduce YMDD mutant and side effects. In 2004 China FDA issued license to manufacture bicyclol. Since then bicyclol has been widely used to treat chronic HBV and HCV in China [1].
Research Area：Infection|Cancer
Targets：Autophagy|HBV
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;
Related Small Molecules:DVR-01;Catalpol;Schisantherin C;HBV-IN-20;Glycosmisic acid;Schisanwilsonin C;RO6889678;Thiamine hydrochloride;Evixapodlin;Canocapavir;HBV-IN-19;Bifendate-d6;(5S,8R)-HBV-IN-10;Punicalin;OSS_128167;3′-DMTr-dG(iBu);HBV-IN-8;HBV-IN-7;L-2′-Fd4C;AB-729;Hepatitis B Virus Core (128-140);Besifovir Dipivoxil maleate;AT-130;HBV-IN-4
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