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BAY-3827
CAS No. : 2377576-35-5
Biological Activity：BAY-3827 is a potent and selective AMPK inhibitor with IC50 values of 1.4 nM at low (10 µM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 shows over 500-fold selectivity for most of the 331 kinases. BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 and shows strongest anti-proliferative activity in androgen-dependent prostate cancer cell lines.
Research Area：Cancer
Targets：AMPK
Related Small Molecules:AMPK activator 4;ZLN024;YLF-466D;3α-Hydroxymogrol;HTH-01-015;TMPA;AICAR;Cimiracemoside C;HL271;EB-3D;COH-SR4;AMPK activator 7;Narazaciclib;D942;MARK4 inhibitor 1;Kazinol U;Phenformin hydrochloride;Karanjin;GSK621;Dorsomorphin;Palmitelaidic Acid;PF-06685249;Flufenamic acid-d4;PF-06679142
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