Atazanavir

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Atazanavir

CAS No. : 198904-31-3

Biological Activity:Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM[3].

Research Area:Infection|Cancer

Targets:HIV|HIV Protease|P-glycoprotein|Endogenous Metabolite|Cytochrome P450|SARS-CoV

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