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Antioxidant agent-5

CAS No. : 2684291-60-7

Biological Activity：Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway.

Research Area：Cardiovascular Disease

Targets：Keap1-Nrf2|NF-κB|Reactive Oxygen Species|Apoptosis

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Icariside F2;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;IKKγ NBD Inhibitory Peptide TFA;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin;Cambinol

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