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AMG PERK 44
CAS No. : 1883548-84-2
Biological Activity：AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy[2].
Research Area：Cancer
Targets：PERK|Autophagy
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Endoplasmic Reticulum Stress Compound Library;Targeted Diversity Library;
Related Small Molecules:GSK2656157;ONO-8130;PERK-IN-3;VU0424465;7DG;ML291;MEK/PI3K-IN-1;Takeda-6D;GSK2606414;PERK-IN-5;PERK-IN-2;MEK/PI3K-IN-2;JDQ-443;MK-28;Derrone;ISRIB (trans-isomer);GSK143 dihydrochloride;YF135;CCT020312;PERK-IN-4-d3;PERK-IN-4
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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