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Afatinib impurity 11
CAS No. : 1402086-20-7
Biological Activity：Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.
Research Area：Cancer
Targets：EGFR|Autophagy
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;Anti-Hepatitis C Virus Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;Genistein;Epertinib hydrochloride;UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202;Avitinib;Naquotinib;Lavendustin A;EAI001;EGFR/HER2/CDK9-IN-2;Cyasterone;DP-C-4;Allitinib
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