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AF-353
CAS No. : 865305-30-2
Biological Activity:AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3[2].
Research Area:Cancer
Targets:P2X Receptor
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cancer Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Targeted Diversity Library;Human Metabolite Library;
Related Small Molecules:Gefapixant citrate;JNJ-47965567;Oxatomide;AZ10606120 dihydrochloride;Taspine;A-317491;NF449 octasodium;A-804598;P2X receptor-1;Aurintricarboxylic acid;Minodronic acid;NF023 hexasodium;A 438079 hydrochloride;KN-62;Opiranserin;GW791343 dihydrochloride;5-BDBD;NF279;Lu AF27139;JNJ-55308942;PPNDS tetrasodium;8-Bromo-ATP;P2X3 antagonist 36;NF110;BAY-1797;Ro-51;P2X3 antagonist 37
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