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(2S)-2′-Methoxykurarinone
CAS No. : 270249-38-2
Biological Activity：(2S)-2′-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2′-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2′-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells[2].
Research Area：Cancer|Metabolic Disease|Inflammation/Immunology
Targets：RANKL/RANK
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-diabetic Compound Library;Lipid Compound Library;Phenols Library;Traditional Chinese Medicine Active Compound Library;Flavonoids Library;Anti-Blood Cancer Compound Library;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;
Related Small Molecules:Cyanidin Chloride;sRANKL-IN-3;Amakusamine;Boldine;sRANKL-IN-1;sRANKL-IN-2
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