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α-Cyano-4-hydroxycinnamic acid
CAS No. : 28166-41-8
Biological Activity:α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications[2].
Research Area:Metabolic Disease
Targets:Monocarboxylate Transporter
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Covalent Screening Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;Cuproptosis Compound Library;
Related Small Molecules:AR-C141990 hydrochloride;MCT1-IN-2;Silychristin;MSC-4381;AR-C155858;7ACC2;AZD3965;BAY-8002;7ACC1;Syrosingopine;VB124
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