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Yoda 1
CAS No. : 448947-81-7
Biological Activity：Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[2][3].
Research Area：Cardiovascular Disease
Targets：Akt|Potassium Channel|Piezo Channel|ERK
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Related Small Molecules:Akt/NF-κB/JNK-IN-1;Kv3 modulator 2;Cyclovirobuxine D;AKTide-2T;Brompheniramine-d6 maleate;Pinacidil;Sennidin A;AMP-PNP tetralithium;MS98;IK1 inhibitor PA-6;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;Corynoxeine;VU590;Domiphen bromide;Artemisiane E;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;Temuterkib;(S)-(+)-Modafinic acid-d5;Artemisinin-d3;Ketanserin;AS1949490;PI3K-IN-29;TD52 dihydrochloride
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