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XL01126
Biological Activity:XL01126 is a potent degrader of LRRK2 with DC50s of 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2), respectively. XL01126 can cross blood-brain barrier and be used as a degrader probe in Parkinson’s disease research. XL01126 exerts function of study of non-catalytic and scaffolding functions of LRRK2.
Research Area:Neurological Disease
Targets:PROTACs|LRRK2
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;LRRK2 inhibitor 1;PROTAC PARP1 degrader;MD-224;FKBP12 PROTAC dTAG-7;SJ10542;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;SJ995973;CC-885-CH2-PEG1-NH-CH3;dFKBP-1;MI-389;BSJ-4-116;MS4078;CZC-25146;PZ703b;DP-C-4;KB02-JQ1;QCA570;NJH-2-056
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