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Vorapaxar sulfate
CAS No. : 705260-08-8
Biological Activity:Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner.
Research Area:Cardiovascular Disease
Targets:Protease Activated Receptor (PAR)
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;FDA-Approved Drug Library; Antiviral Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;EMA-Approved Drug Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:ENMD-1068 hydrochloride;Atopaxar hydrobromide;SLIGRL-NH2 TFA;SCH79797 dihydrochloride;AC-55541;TRAP-6-IN-1;TRAP-6 amide TFA;I-191;ML354;Parstatin(human);UDM-001651;AZ8838;Protease-Activated Receptor-1, PAR-1 Agonist;TFLLR-NH2(TFA);tcY-NH2;VKGILS-NH2 TFA;2-Furoyl-LIGRLO-amide TFA;Protease-Activated Receptor-1 antagonist 1;GB-110;Protease-Activated Receptor-1 antagonist 2;RWJ-56110 dihydrochloride;Trypsin;TRAP-6;Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA;GB-88
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