Vonoprazan Fumarate

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Vonoprazan Fumarate

CAS No. : 881681-01-2

Biological Activity:Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease[2].

Research Area:Metabolic Disease

Targets:Proton Pump

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