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VGX-1027
CAS No. : 6501-72-0
Biological Activity：VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties. VGX-1027 targets macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, IL-10. VGX-1027 has antidiabetogenic effects by limiting cytokine-mediated immunoinflammatory events[2][3].
Research Area：Metabolic Disease|Inflammation/Immunology
Targets：TNF Receptor|Interleukin Related
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Clinical Compound Library;Differentiation Inducing Compound Library;Anti-diabetic Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;AX-024;Ginsenoside F3;Perakizumab;PNRI-299;QNZ;CTX-471;Ac-YVAD-CHO;Sinulatumolin E;Deucravacitinib;Epobis;Mulberroside A;Sinulatumolin D;NFAT Transcription Factor Regulator-1;PDE4-IN-10;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;TIC10;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Teneliximab;Anti-Mouse IL-1b Antibody;Raleukin;Loganic acid 6′-O-β-D-glucoside;Ossirene;RCGD423
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