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Verosudil
CAS No. : 1414854-42-4
Biological Activity：Verosudil (AR-12286) is a potent, selective Rho-kinase (ROCK) inhibitor with Kis of 2 and 2 nM for ROCK1 and ROCK2, respectively. AR-12286 lowers intraocular pressure (IOP) primarily by increasing aqueous humour outflow through the trabecular meshwork[2].
Research Area：Neurological Disease
Targets：ROCK
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Cytoskeleton Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Ripasudil free base;PF-4950834;ROCK-IN-4;GSK-25;AT13148;LX7101;Y-27632 dihydrochloride;RKI-1447;AS1892802;SB-772077B dihydrochloride;BDP5290;Fasudil;3-(4-Pyridyl)indole;GSK429286A;CRT0066854;H-1152 dihydrochloride;ROCK2-IN-5;Cotosudil;ZINC00881524;Hydroxyfasudil hydrochloride;HA-100 hydrochloride;Thiazovivin;Rho-Kinase-IN-1;Y-33075;BAY-549
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