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TyK2-IN-2
CAS No. : 2098466-94-3
Biological Activity：TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TyK2-IN-2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases.
Research Area：Inflammation/Immunology
Targets：Phosphodiesterase (PDE)|JAK
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:Senazodan hydrochloride;AZ-3;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;JAK3/BTK-IN-1;ATX inhibitor 22;Carbazeran citrate;AT9283;Benzene hexabromide;Bay 60-7550;BC11-38;(E/Z)-Zotiraciclib;Deltarasin hydrochloride;JAK-IN-10;Glaucine;Baricitinib-d3;JAK3-IN-6;Ziritaxestat;Udenafil-d7;D159687;ITI-214;Coumermycin A1;Deucravacitinib;PDE10-IN-5;Momelotinib-3,3,5,5-d4
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