TYK2-IN-12

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TYK2-IN-12

CAS No. : 2244061-66-1

Biological Activity:TYK2-IN-12 (compound 30) is an orally active, potent and selective TYK2 (tyrosine kinase 2) inhibitor, with a Ki of 0.51 nM. TYK2-IN-12 inhibits IL-12 induced IFNγ, with IC50 values of 2.7 and 7.0 μM in human and mouse whole blood, respectively. TYK2-IN-12 can be used for psoriasis research.

Research Area:Inflammation/Immunology

Targets:IFNAR|JAK

Related Small Molecules:AZ-3;AX-024;JAK3/BTK-IN-1;Cirsilineol;AT9283;Benzene hexabromide;Ginsenoside F3;(E/Z)-Zotiraciclib;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SJ10542;Delgocitinib;Upadacitinib;α7 nAchR-JAK2-STAT3 agonist 1;Filgotinib-d4;AZD-1480;JAK-IN-20;JAK3 covalent inhibitor-1;JAK3-IN-12;(R)-Reticuline-d3;JAK-IN-23

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