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Tubulysin
CAS No. : 1943604-24-7
Biological Activity:Tubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system.
Research Area:Cancer
Targets:Microtubule/Tubulin
Related Small Molecules:Tirbanibulin dihydrochloride;Tilavonemab;Tau tracer 1;Dolastatin 10;Ceratamine A;Batabulin sodium;OXi8007;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Oryzalin;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;Tubulin inhibitor 16;Epothilone B;TN-16;Maytansinol;VcMMAE;Mc-MMAE;SS28;Tubulysin H;Fosbretabulin disodium;Tubulin polymerization-IN-7
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