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Tomatine
CAS No. : 17406-45-0
Biological Activity：Tomatine is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.
Research Area：Neurological Disease
Targets：Proteasome|Apoptosis
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