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TH1217
CAS No. : 1862212-48-3
Biological Activity：TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19[2].
Research Area：Cancer|Infection
Targets：SARS-CoV
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B;Proglumetacin;HCoV-229E-IN-1
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