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SRI 31215 TFA
CAS No. : 1832686-44-8
Biological Activity：SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer.
Research Area：Cancer
Targets：c-Met/HGFR
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Anti-Lung Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:AMG-208;D6808;MET kinase-IN-2;c-Met-IN-9;Tyrosine kinase-IN-4;Savolitinib;Foretinib;PF-04217903 phenolsulfonate;MK-2461;XL092;SAR125844;MK-8033 hydrochloride;BPI-9016M;Ficlatuzumab;Meleagrin;c-Met inhibitor 1;Pamufetinib;PHA-665752;c-Met/HDAC-IN-2;SU11274;Antitumor agent-45;Capmatinib hydrochloride;SCR-1481B1;SYN1143;Amuvatinib hydrochloride;c-Met/HDAC-IN-3;Gemnelatinib
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