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SR-717 free acid
CAS No. : 2375420-34-9
Biological Activity：SR-717 free acid is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity.
Research Area：Cancer|Inflammation/Immunology
Targets：STING
Related Small Molecules:STING agonist-3 trihydrochloride;BSP16;IACS-8803 diammonium;STING-IN-2;STING agonist-10;CDN-A;STING agonist-20;MSA-2;TAK-676;ADU-S100 ammonium salt;H-151;STING ligand-1;cGAMP;Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine;diABZI STING agonist-1;JAK-IN-23;Ulevostinag;Cyclic-di-GMP;2′,3′-cGAMP sodium;STING agonist-16;E7766 disodium;STING agonist-4;STING agonist-17;SN-001
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