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Sorafenib-13C,d3
CAS No. : 1210608-86-8
Biological Activity：Sorafenib-13C,d3 is the 13C- and deuterium labeled Sorafenib. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator.
Research Area：Cancer
Targets：Ferroptosis|FLT3|Autophagy|Raf|VEGFR|Apoptosis
Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;CIL56;DB0614;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Avutometinib;Lobetyolin;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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