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SKLB-197

CAS No. : 2713577-16-1

Biological Activity：SKLB-197 showed an IC₅₀ value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.

Research Area：Cancer

Targets：ATM/ATR

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;

Related Small Molecules:ATR-IN-16;ATR-IN-4;CGK733;Ceralasertib;KU 59403;ATM Inhibitor-1;ATR-IN-5;ATR inhibitor 1;VE-821;KU-55933;Garcinone C;ATR-IN-18;AZD0156;CP-466722;Mirin;ATR-IN-13;Antitumor agent-28;ATR-IN-11;ATR-IN-8;AZ31;ATR-IN-12;ATR-IN-20;ATM Inhibitor-2;Elimusertib;Ro 90-7501;Gartisertib;ATR-IN-7;ATR-IN-17;KU-60019

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