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SK1-I
CAS No. : 1072443-89-0
Biological Activity：SK1-I (BML-258), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 µM. SK1-I shows no activity at SPHK1 PKCα, PKCδ, PKA, AKT1, ERK1, EGFR, CDK2, IKKβ or CamK2β. SK1-I enhances autophagy and has antitumor activity[2].
Research Area：Cancer
Targets：SphK
Related Small Molecules:SphK2-IN-2;SphK1-IN-3;MHP;PF-543 Citrate;SKI V;Phorbol 12-myristate 13-acetate;SKI II;Peretinoin;Amgen-23;SLP9101555;SphK1-IN-1;MP-A08;CAY10621;K145 hydrochloride;SKI-178;K6PC-5;Opaganib;SphK2-IN-1;SK1-IN-1;SLM6031434 hydrochloride;SphK1-IN-2;SKI-I
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