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SirReal1-O-propargyl
CAS No. : 1862237-99-7
Biological Activity：SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2.
Research Area：Cancer
Targets：Ligands for Target Protein for PROTAC
Related Small Molecules:BI-4464;PROTAC BRD4 ligand-2;PROTAC BRD9-binding moiety 1 hydrochloride;PROTAC IRAK4 ligand-1;Apcin-A;Ipatasertib-NH2 dihydrochloride;PD0325901-O-C2-dioxolane;CDK9-IN-10;TSPO ligand-1;SLF TFA;PROTAC Bcl-xL ligand-1;ATRA-hydroxyimino;HG-7-85-01-Decyclopropane;MAK683-CH2CH2COOH;DUPA;Abemaciclib metabolite M18;PROTAC PTK6 ligand-1;PROTAC BRD9-binding moiety 5;SLF-amido-C2-COOH;AP1867-3-(aminoethoxy);SMARCA-BD ligand 1 for Protac dihydrochloride;Ch55-O-C3-NH2;PROTAC PARP/EGFR ligand 1;PROTAC BET-binding moiety 1
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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