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Seltorexant hydrochloride
CAS No. : 1293284-49-7
Biological Activity：Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.
Research Area：Endocrinology|Neurological Disease
Targets：Orexin Receptor (OX Receptor)
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;Targeted Diversity Library;Children’s Drug Library;
Related Small Molecules:MK-3697;JNJ-54717793;TCS-OX2-29;IPSU;Orexin B, rat, mouse;SB-649868;Orexin A (human, rat, mouse) (acetate);SB-408124 Hydrochloride;OX2R-IN-1;EMPA;Orexin B, human;SB-334867 free base;MK-1064;Almorexant-13C,d3;YNT-185 dihydrochloride;Orexin 2 Receptor Agonist;[Ala11,D-Leu15]-Orexin B(human);Suntinorexton;Almorexant;SB-674042;Filorexant;Orexin receptor antagonist 4;OXA(17-33) TFA;Lemborexant;Danavorexton
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