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Rosiglitazone-d3
CAS No. : 1132641-22-5
Biological Activity：Rosiglitazone-d3 (BRL 49653-d3) is the deuterium labeled Rosiglitazone. Rosiglitazone (BRL 49653) is a selective, orally active PPARγ agonist with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. Rosiglitazone binds to PPARγ with a Kd of approximately 40 nM. Rosiglitazone is also an activator of TRPC5 (EC50=~30 μM) and an inhibitor of TRPM3[2][3][4].
Research Area：Cancer|Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets：Ferroptosis|Autophagy|TRP Channel|PPAR
Related Small Molecules:V116517;CIL56;DB0614;GSK2332255B;Pregnenolone monosulfate sodium;Ciclopirox-d11;Ciclopirox olamine;Curcumin;TRPC5-IN-4;OptoBI-1;Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;SB-705498;PPARγ agonist 7;TRPC3/6-IN-1;ABT-239;Pyr3;Licarin B;Asivatrep;(-)-Epicatechin;Mifobate;Eugenol-d3
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