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Rocaglamide

CAS No. : 84573-16-0

Biological Activity：Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC₅₀ of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia^[2]^[3].

Research Area：Cancer

Targets：NF-κB|HSP|Eukaryotic Initiation Factor (eIF)

Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;6BrCaQ;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;116-9e;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Paeoniflorin;HDAC/HSP90-IN-4;Berbamine;Debio 0932;NF-κΒ activator 2;MKT-077;20(S)-Ginsenoside Rg3;Ethoxyquin;Ginsenoside Rd

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